# American Cancer Society Discovery Shop - Los Altos, CA: Thrift Store in Los Altos, CA

> American Cancer Society Discovery Shop - Los Altos, CA is a thrift store in Los Altos, CA.

Source: https://thriftnearby.com/ca/los-altos/american-cancer-society-discovery-shop-los-altos-ca/

This thrift boutique at 243 Main St supports the American Cancer Society, with proceeds funding cancer research and support programs. The shop sells donated clothing, housewares, books, jewelry, and vintage items, and reviewers note designer clothes, collectibles, crystal, and gifts. Shoppers can donate gently used goods. Open six days a week, the store accepts credit and debit cards and offers wheelchair accessible entrance and parking.

> We are the American Cancer Society Discovery Shop—your local thrift boutique with a vision to end cancer as we know it, for everyone. Shop high-quality donated finds, give back, and help fight cancer. Every purchase, donation, and volunteer hour fuels research, support programs, and hope. Shop local. Make an impact. SHOP Discover high-quality, donated clothing, housewares, books, and more—carefully curated just for you. There’s always something special to find. DONATE Clean out with purpose. Donate gently used items to support the American Cancer Society’s mission. VOLUNTEER Join our…
>
> — From the store’s Google listing

## Details

- Type: Thrift Store
- Address: 243 Main St, Los Altos, CA 94022
- Phone: +1650-949-0505
- Website: https://acsdiscoveryshop.com/los-altos-discovery-shop/
- Google rating: 4.8 from 80 reviews
- County: Santa Clara County
- Map: https://www.google.com/maps/search/?api=1&query=37.3784093,-122.115994
- Last verified: 2026-09-20
- Star breakdown: 5★ 70, 4★ 5, 3★ 3, 2★ 0, 1★ 2

## Features

- Buying and donating: Sells used goods, Accepts clothing for recycling or donation
- Accessibility: Wheelchair accessible entrance, Wheelchair accessible parking
- Payments: Credit cards, Debit cards

## What reviewers mention

jewelry (7), designer clothes (5), housewares (5), vintage items (4), gift selection (3), collectibles (2), crystal (2), treasure hunt (2)

## Hours

- Monday: 10:00 AM – 6:00 PM
- Tuesday: 10:00 AM – 6:00 PM
- Wednesday: 10:00 AM – 6:00 PM
- Thursday: 10:00 AM – 6:00 PM
- Friday: 10:00 AM – 6:00 PM
- Saturday: Closed
- Sunday: 10:00 AM – 5:00 PM

## Nearby thrift stores

- [Eco-Fash](https://thriftnearby.com/ca/los-altos/eco-fash/): Thrift Store · 251 Main St, Los Altos, CA 94022 · 3.3★ (7 reviews) · +1650-559-0250 · 0.0 km away
- [Serene Junk Hauling Services](https://thriftnearby.com/ca/los-altos/serene-junk-hauling-services/): Second Hand Shop · 180 2nd St, Los Altos, CA 94022 · 5★ (1 reviews) · +1650-772-9849 · 0.1 km away
- [Encore Round Robin](https://thriftnearby.com/ca/los-altos/encore-round-robin/): Consignment Shop · 146 Main St Ste 1A, Los Altos, CA 94022 · 3.5★ (11 reviews) · +1650-948-0955 · 0.2 km away
- [Repeter](https://thriftnearby.com/ca/los-altos/repeter/): Consignment Shop · 308 State St, Los Altos, CA 94022 · 4.1★ (13 reviews) · +1650-949-1323 · 0.2 km away
- [Goodwill of Silicon Valley](https://thriftnearby.com/ca/palo-alto/goodwill-of-silicon-valley/): Thrift Store · 4085 El Camino Way, Palo Alto, CA 94306 · 3.8★ (425 reviews) · +1650-494-1416 · 4.2 km away

## More

- [All thrift stores in Los Altos, CA](https://thriftnearby.com/ca/los-altos/)

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